F2 and Rickettsiosis: Likewise, for the patient cohort described in this manuscript, the total rickettsiosis, ehrlichiosis, and coinfection cases are consistent with previous reports that describe an increase in hepatic enzymes (ALT, AST, and AP), clinical chemical analytes with alterations, such as an increased clotting time (CT), prothrombin time (PT), and partial thromboplastin time (PTT).