The top 5 enriched pathways according to the adjusted p value were rheumatoid arthritis (hsa05323), the TNF signaling pathway (hsa04668), the IL-17 signaling pathway (hsa04657), the AGE-RAGE signaling pathway in diabetic complications (hsa04933), fluid shear stress and atherosclerosis (hsa05418). This evidence concerns the gene TNF and atherosclerosis.