The importance of determining biomarkers in the blood of patients with CDI was also confirmed by Herbert et al., who showed that CRP values were statistically significantly higher in patients with CDI compared to patients with CD-toxin-negative diarrhea (126 mg/L vs. 58.5 mg/L, p = 0.001) and that albumin values were statistically significantly lower in patients with CDI compared to patients with CD-toxin-negative diarrhea (22 g/L vs. 25 g/L, p = 0.003) [36]. Here, CRP is linked to clostridium difficile infection.