PPARA and diabetic cardiomyopathy: Thirty-three KEGG pathways were annotated in SD (Figure 4D,E and Table S6); 16 pathways that were enriched, such as oxidative phosphorylation (NES = 2.7144), chemical carcinogenesis—reactive oxygen species (NES = 2.4081), and diabetic cardiomyopathy (NES = 1.9715), and 17 pathways were suppressed, such as propanoate metabolism (NES = −1.8942), fatty acid metabolism (NES = −1.9656), PPAR signaling pathway (NES = −2.2145), and regulation of lipolysis in adipocytes (NES = −2.3714).