On the basis of the results on increased ovarian cancer risk in GSTP1*Ile (referent) allele carriers, it might be speculated that the stronger GSTP1:JNK interaction, which includes participation of GSTP1-risk associated allele, could prevent activation of apoptosis of ovarian cancer cells in these women, further affecting the progression of disease [51]. Here, MAPK8 is linked to ovarian cancer.