García-Giménez and collaborators found that miR-1306-3p targeted the protein serine/threonine phosphatase 2CB, which participates in the TGFβ signaling pathway, which has already been shown to be involved in AIS, as an increased expression of TGF-β2, TGF-β3 and TGFBR2 (encoding for a TGFβ receptor) was found in samples from the curve concavity of AIS patients [67] and it was reported that TGFB1 may play a role in the curve progression of AIS [68]. Here, TGFB3 is linked to androgen insensitivity syndrome.