PIK3CA and adenocarcinoma: EGFR (Arg255Gln), EGFR (Ala647Thr), EGFR (Leu858Arg), KRAS (Gly12Cys), ALK (Pro254Thr), ALK (Trp288Ser), ALK (Glu797Lys), ROS (Glu1902Lys), PIK3CA (Met1043Ile), ROS (Leu567Val), and ROS (Phe1153Leu) mutations were present only in patients with adenocarcinoma.