UPF1 and nonpapillary renal cell carcinoma: In order to investigate the potential mechanism of UPF1 in ccRCC, the GSVA algorithm was used to screen out the most important signaling pathways by comparing Immport and Reactome pathway activities between the low UPF1 group and the high UPF1 group, which indicated that the high-UPF1 group was enriched in cytokine receptor interaction.