We propose that these enriched HAR and PS genes (EIF4E, EIF5, EIF3M, DDX17, SRSF11, PSPC1, SUMO1, CAPZA1, PSMD14, and MNAT1) and the highly connected hub genes HNRNPA1, RBMX, PRKDC, and RANBP2 are key genes for both diagnostic biomarkers in preeclampsia and therapeutic intervention targets. Here, MNAT1 is linked to preeclampsia.