MANOVAs showed significant main effects for CACNA1C rs2283274 (GG vs. CG vs. CC) (F(12,138) = 1.865, p = 0.045) and rs2239063 (AA vs. AC vs. CC) (F(12,138) = 1.900, p = 0.039) in unmedicated patients with schizophrenia, but not in controls. Here, CACNA1C is linked to schizophrenia.