Several other critical proteins linked to neurodegenerative diseases have also been experimentally validated as CaMBPs, including APOE (AD, FTD, PD, LBD), calcineurin (PP2B; AD, FTD, PD, HD, MS), CaMKII (AD, FTD, PD, HD), and many others [10,18]. Here, APOE is linked to Alzheimer disease.