The colonic mRNA expressions of TNF-α, IL-1β, IL-6, MyD88, and NF-κB genes were higher (p < 0.05) in IUGR lambs than in the CON lambs but were lower (p < 0.05) in Arg-or NCG-supplemented IUGR lambs compared to the untreated IUGR ones (Table 4). Here, TNF is linked to fetal growth restriction.