Notably, Gholami et al. (2021) identified miR-182-5p, miR-192-5p, miR-204-5p and miR-493-5p as part of a regulatory network of cystein-rich secretory protein 3 (CRISP3) isoforms in spermatozoa from men with teratozoospermia and proposed overexpressed miR-182-5p, miR-192-5p and miR-493-5p as putative biomarkers of teratozoospermia [38]. The gene discussed is CRISP3; the disease is Abnormal sperm morphology.