IFNG and Miyoshi myopathy: MM cells secrete GM3 ganglioside, which together with the high levels of CD1d expression in the BM microenvironment, results in the formation of the CD1d/GM3 complex, which binds to the invariant T-cell receptor of iNKT resulting in iNKT deregulation, loss of IFNγ secretion, and immune evasion [109].