PDAC: pancreatic ductal adenocarcinoma; ANGPTL4: Angiopoietin-like 4 (ANGPTL4); ICAM-1: intercellular adhesion molecule-1; KLF4: Krüppel-like factor 4; PanIN: pancreatic intraepithelial neoplasia; SOX9: SRY (sex-determining region Y)-box 9. Here, ICAM1 is linked to pancreatic ductal adenocarcinoma.