In the literature, histological subtypes that have been previously highlighted as precursor lesions include intraductal papillary mucinous neoplasm (IPMN), a mucin-producing subtype arising from the pancreatic duct system and mucinous cystic neoplasm (MCN), characterized by the presence of ovarian-type stroma [81]. This evidence concerns the gene MUC5AC and pancreatic intraductal papillary-mucinous neoplasm.