POGK and hepatocellular carcinoma: After stratifying based on clinical characteristics, high POGK expression was significantly associated with poor prognosis in HCC patients with pathologic stages 2 and 3 (p = 0.027), pathologic stages 3 and 4 (p = 0.0028), pathologic stage 3 (p = 0.0053), T3 stage (p = 0.00089), histologic grade 1 (p = 0.00086), male gender (p = 0.0014), absence of history of HBV infection (p = 0.00073), and history of alcohol intake (p = 0.03) (Figure 4E–T).