ARID1A and malignant colon neoplasm: Because VIM expression was upregulated in the absence of ARID1A, which was associated with shorter survival in colon cancer patients, we examined VIM expression in colon cancer cell lines and found that VIM expression is high in cells with low ARID1A expression (SW620&RKO) and low in cells with a high ARID1A expression (HCT116&LoVo) (Figure 2C).