IgG autoantibodies against HDL and apoliprotein A-I (ApoA-I) are increased in SLE patients in a study including 77 SLE patients and paired controls, showing that the presence of IgG anti-HDL and Apo A-I produced destabilization of the atheromatous plaque (96). Here, APOA1 is linked to systemic lupus erythematosus.