Furthermore, the percentages of PD-1+CD39+CD103+CD8+T (p = 0.0022) and PD-1+CD39+CD103-CD8+T (p = 0.001) cells were significantly higher in recurrence tumor than non-recurrence tumor, and this phenomenon was seen for the density of these two CD8+T-cell subsets (p = 0.0178 for PD-1+CD39+CD103+CD8+T cells, p = 0.0332, for PD-1+CD39+CD103-CD8+T cells, Figures 4C, D). This evidence concerns the gene ENTPD1 and neoplasm.