FAM161A and retinitis pigmentosa: Retinitis pigmentosa is genetically and clinically heterogeneous and can be caused by pathogenic variants in > 270 genes (RetNet, https://sph.uth.edu/retnet/), 1 of them being FAM161A. After the identification of FAM161A in 20106,7 as a cause of RP, it was found to encode a ciliary protein localized to the base of the connecting cilium and is also expressed in the inner segments (ISs) of photoreceptor cells, the inner and outer plexiform layers (OPLs), and the ganglion cell layer of the retina.8