As we found previously (Marqués-Torrejón et al., 2021), endogenous EGFR protein was reduced in Lrig1 KO cells compared to Lrig1 WT, even under proliferative conditions (EGF/FGF) (we have observed this lack of EGFR band to occur in other tumour lines when the receptor is very active). Here, EGF is linked to neoplasm.