ADRA2A and type 2 diabetes mellitus: We used lentivirus-mediated RNA interference to decrease the expression of Adra2a in T2D ASCs to determine the specific function of this receptor in ASCs and found that the expression and secretion of growth factors in Adra2a knocked-down T2D ASCs were significantly higher than that of T2D ASCs, and after Adra2a knockdown, the T2D ASC treatment groups did not work on the stimulation of clonidine.