By detecting the expression of growth factors and inflammatory factors in the 4 groups of T2D mice on the 14th day, we found that the relative expression of VEGF and TGF-β in the T2D+C57BL/6 ASC and T2D+knockdown T2D ASC groups was higher than the PBS and T2D ASC treatment groups. This evidence concerns the gene TGFB1 and type 2 diabetes mellitus.