The targets plk2, mmp2, aldh4a1 and crip2, cdkn1a (p21) are associated with suppression of apoptosis, tumor growth, and oxidative stress response, but not with cell death (Seoane et al., 2002; Miyake et al., 2015; Han et al., 2018). Here, ALDH4A1 is linked to neoplasm.