To confirm the expression of these ICD-related genes in melanoma, we compared these 23 ICD-related genes that differed between melanoma and normal samples, with a total of eight genes significantly different (PRF1, LY96, ILR1, HSP90AA1, CD8A, CD4, CALR, CXCR3), as shown in Figure 2B. This evidence concerns the gene CALR and melanoma.