CD79A and breast carcinoma: In another case-control study, Goedert and colleagues (117) investigated the role of immunity and inflammation in breast cancer risk and whether the gut microbiota differed in the composition of the immune recognition microbiota and found significant differences in the composition, abundance and alpha diversity of the microbiota between the IgA+ and control IgA- groups in cancer cases and correlated with changes in high and low estrogen levels.