Significant associations between MHR, MAR and osteoporosis were also observed after further adjustment for BMI, HbA1c, BMI, TG, HDL-c, LDL-c, creatinine, ALT, UA, HOMA-IR (Model 5), the ORs (95%CI) were 1.92 (1.52–2.44) and 2.68 (2.03–3.55) respectively. This evidence concerns the gene GPT and osteoporosis.