After further controlling for the use of LLDs, IIAs, and metformin (model 2), SBP, DBP, and BMI (model 3), ALT, LDL-C, TC, eGFR, SUA, HbA1c, FPG, 2h PPG, FCP, 2h PCP, UAE, and CRP (model 4), WHtR was still independently correlated with the presence of MetS in both men (model 2: OR = 7.883, 95% CI: 6.864–9.054; model 3: OR = 5.127, 95% CI: 4.310–6.099; model 4: OR = 4.821, 95% CI: 3.949–5.885; respectively, all p < 0.001) and women (model 2: OR = 5.081, 95% CI: 4.413–5.850; model 3: OR = 2.926, 95% CI: 2.437–3.514; model 4: OR = 3.096, 95% CI: 2.484–3.860; respectively, all p < 0.001). This evidence concerns the gene GPT and metabolic syndrome.