FGFR4 and hepatocellular carcinoma: Notably, the STRING analysis of these 55 genes with differential expression and altered splicing pattern revealed the existence of 3 gene clusters implicated in RNA splicing, metabolism and translational initiation (Figure 5E), the former one including relevant genes in HCC such as FGFR4, the FGF19 receptor, which has been reported to exert oncogenic roles in HCC.24