NBN and cancer: Moreover, ATV shows synergistic antiproliferative, antiangiogenic, and apoptotic actions against various types of cancers (e.g., colon, lung, and prostate), in combination with anticancer agents such as doxorubicin, cisplatin, paclitaxel, topotecan, bevacizumab, and celecoxib (Zheng et al., 2010; Buranrat et al., 2017; Tan et al., 2017; Ma et al., 2019; Guo et al., 2020; Lee et al., 2021; Marti et al., 2021).