In relation to survival, studies show that males with AML exhibit higher rates of RUNX1, ASXL1, SRSF2, BCOR, U2AF1, EZH2, and ZRSR2 mutations, while females have higher rates of FLT3‐ITD, NPM1, and DNMT3A, concluding that this sex have more high‐risk somatic mutations.9, 30. This evidence concerns the gene NPM1 and acute myeloid leukemia.