Metformin and Nifedipine (17.4%); Spironolactone Tab and Hydrochlorothiazide (HCT) (13.2%); Glimepiride and Enalapril (9.3%); and Insulin and Nifedipine (8.9%) were the most often utilized medications for the management of diabetes complications among the patients in the study area (Table 3). This evidence concerns the gene INS and diabetes mellitus.