In the FinnGen general population GWAS data, among the significant or replicated variants within the lead genes, the LIPC p.Ser301Phe variant, as well as the TRMT5 p.Ala456Val and p.Ser185Cys variants, was associated with the stroke and CVD phenotypes (LIPC p.Ser301Phe p=0.0024 for the wide stroke definition; TRMT5 p.Ser185Cys p=0.0010 for the wide stroke definition; Table 5). Here, TRMT5 is linked to stroke disorder.