Second, due to the fact that differentiated thyroid cancer harbors an excellent prognosis compared to other cancers and the small number of cancer specimen in our TMA cohort, we were not able to evaluate the prognostic relevance of CXCR4, pCXCR4, SDF-1 and CD8+ in this cohort. This evidence concerns the gene CXCR4 and thyroid gland carcinoma.