AKT1 and central nervous system cancer: Wang et al. [10] also reported that FAM84B expression is elevated in glioma specimens, which is associated with low survival in patients, and the silencing of FAM84B can inhibit the proliferation and invasion of glioma cells by regulating the Akt/GSK-3β/β-catenin pathway, thus inducing the apoptosis of glioma cells.