LRATD2 and central nervous system cancer: FAM84B expression was detected by qRT-PCR in the human glioma cell lines, U251, T98, LN-229, and U87, showing the highest expression in U87 cells, P < 0.05, as shown in Fig. 3A. In order to ensure the universality of the research results, U87 and T98 cells were taken to transfect two FAM84B siRNAs for subsequent functional experiments.