APOA5 and metabolic syndrome: Additionally, rs117026536 in the LPL gene, rs651821 in the APOA5 gene, rs9926440 in the CETP gene, and rs429358 in the APOE gene were associated with dyslipidemia.The GWAS analysis of the male subjects revealed 13 significant SNPs in the discovery stage (P < 5 × 10− 8) (Fig. 1B).