DNAJC5 and hepatocellular carcinoma: Based on the successful construction of the recombinant protein (rES-CSP) in the early stage, which has the ability to inhibit angiogenesis and could specifically bind to hepatocellular carcinoma, this study will further verify the role of rES-CSP in inhibiting hepatocellular carcinoma metastasis in vitro and in vivo; On the other hand, the underlying mechanism of anti-metastasis will be discussed.