CD4 and cancer: In the R_cancer patients, the proportions of ‘T cell CD8’, ‘T cells CD4 naïve’, ‘T cells follicular helper’, ‘Mast cells resting’ were significantly higher and ‘B cells memory’, ‘macrophages M0’ were lower than in L_cancer patients (Wilcoxon test, all P < 0.05; Fig. 3A).