Related genes including ENG, PIEZO2, BMP6, KCNJ2, TLR4, IGF1R, THBS1, HIF1a, GRIA4, CNGB3, VIP, DRD2 and TRPV1. Excluding myopia, atropine had four GO clusters related to astrocytes. The gene discussed is HIF1A; the disease is myopia.