There are two main types of DM depending on the insulin secretory function of the pancreas: type 1 DM (T1DM), which is characterized by a complete lack of insulin secretion and frequently occurs in children and adolescents, and type 2 DM (T2DM), which frequently occurs in adults and results mainly from reduced insulin secretion and function [3]. The gene discussed is INS; the disease is type 1 diabetes mellitus.