In 2001, Bautista et al. [6] found that CRP levels remained strongly associated with hypertension and first clearly proposed CRP concentrations as an independent risk factor for hypertension, but this finding was numerous questioned due to the small sample size of their study and the fact that the prevalence of hypertension was as high as 46%, higher than the prevalence at that time. The gene discussed is CRP; the disease is hypertensive disorder.