Our study found a higher proportion of alcohol consumption in the group with elevated CRP (P < 0.05), which is similar to the findings of a recent cohort study of Chinese men aged 50 years and older [33], which showed that compared with never and occasional drinkers (< 1 drink/week), daily (OR = 1.38, 95% CI: 1.24–2.65) and excessive drinkers (weekly ethanol intake ≥ 210 g, OR = 1.57, 95% CI: 1.22–2.02) had a higher risk of elevated CRP and a higher risk of cardiovascular disease, and therefore patients are advised to drink less or even abstain from alcohol. The gene discussed is CRP; the disease is cardiovascular disorder.