In our study, we found that in the elderly population, blood pressure levels were significantly higher in the group with elevated CRP than in the normal group, and the prevalence of hypertension was higher in the group with elevated CRP than in the normal group, with statistically significant differences (P < 0.05), and logistic regression also showed an independent positive association between elevated CRP and the risk of hypertension (OR = 2.13, 95% CI: 1.14–3.99, P < 0.05). The gene discussed is CRP; the disease is hypertensive disorder.