The CYP2E1 rs3813867 polymorphism was not significantly associated with CRC risk in any of the genetic models studied (homozygous model, OR = 1.020, 95% CI 0.682–1.526, P = 0.923; heterozygous model, OR = 1.161, 95% CI 0.841–1.603, P = 0.366; dominant model, OR = 1.179, 95% CI 0.845–1.645, P = 0.333; recessive model, OR = 1.302, 95% CI 0.693–1.538, P = 0.876; allele model, OR = 1.175, 95% CI 0.862–1.602, P = 0.306) (Fig. 3). This evidence concerns the gene CYP2E1 and colorectal carcinoma.