EZH2 and hepatocellular carcinoma: For example, PLANE regulates NCOR2 AS by forming an RNA–RNA duplex with NCOR2 pre-mRNA to promote cancer pathogenesis [37]; LINC01348 suppresses hepatocellular carcinoma metastasis by inhibiting SF3B3-mediated EZH2 pre-mRNA splicing [38], and DGCR5 promotes oncogenesis in esophageal squamous cell carcinoma via SRSF1-mediated AS of Mcl-1 [39].