In parallel, immunostaining showed that the proportion of ALDH1+ breast cancer cells was considerably higher in the xenografts formed by MCF-7 cells coinjected with NBFs and treated with CCL18 (Fig. 6B and Supplementary Fig. 6A), and the mice harboring these tumors also had a greater abundance of CD10+GRP77+ fibroblasts (Fig. 6B and Supplementary Fig. 6A). Here, MME is linked to breast cancer.