To further evaluate the correlation between CCL18+ TAMs and CD10+GPR77+ CAFs, we analyzed single-cell RNA sequencing (scRNA-seq) data for 46 cases of treatment-naive breast cancer from GEO series GSE161529 and 14 cases of treatment-naive breast cancer from the pancancer TME blueprint (https://lambrechtslab.sites.vib.be/en/pan-cancer-blueprint-tumour-microenvironment-0). The gene discussed is C5AR2; the disease is breast carcinoma.