The top 20 genes (SRSF2, HNRNPK, DDX5, KHDRBS1, DHX15, HNRNPH3, HNRNPA0, RBM25, XPO1, MBNL1, PTEN, SMAD4, RPS6KB1, RBM15, ATM, DDX21, PPP1CC, CDKN1B, TGFBR2, BCLAF1) are shown in Fig. 2B. Further, a PPI network was made for FTD-related modules. This evidence concerns the gene SMAD4 and frontotemporal dementia.