The genes in modules non-preserved in FTD disease, including lightgreen, midnightblue, and purple modules, were enriched in ‘prion disease’, and pathways related to metabolic disorders such as ‘diabetic cardiomyopathy’, ‘insulin signaling pathway’, and ‘aldosterone synthesis and secresion’ (Fig. 3b). Here, INS is linked to diabetic cardiomyopathy.