Furthermore, the analysis revealed that DMR-associated genes were enriched in ‘regulation of parathyroid hormone secretion’, ‘regulation of synaptic activity’ and highly overlapping with genes involved in ‘phospholipase D signaling pathway’, ‘adrenergic signaling in cardiomyocytes’ and ‘Parkinson disease’ (Supplementary Fig. 5c). This evidence concerns the gene PTH and Parkinson disease.