Analysis of the protein groups identified in each cell line revealed that there were more Kpnβ1 binding partners in the cancer cell extracts compared to the normal cell extracts: 100 proteins were identified as potential binding partners of Kpnβ1 in normal hTERT-RPE1 cell extracts, while 179 proteins were pulled down with Kpnβ1 in HeLa cells, and 147 and 176 proteins were pulled down with Kpnβ1 in WHCO5 and KYSE30 oesophageal cancer cells, respectively (Supplementary fig. This evidence concerns the gene KPNB1 and carcinoma of esophagus.