P2RX1 and acute myeloid leukemia: Because P2X1 can be phosphorylated at several phosphorylation sites [42], including S387, S388 and T389, we investigated whether these phosphorylation sites play a role in AML development by mutating the abovementioned P2X1 phosphorylation sites (Table S2) and evaluating their potential effects on leukemogenesis.