PTGS2 and non-small cell lung carcinoma: In addition, the expression of PTGS2, a maker gene of ferroptosis, as well as lipid peroxidation, were measured using qPCR and BODIPY staining respectively, and the results also showed a similar tendency as MDA and 4-HNE in different groups (Fig. 2D, E), suggesting that the sensitivity of NSCLC cells to the ferroptosis induced by cysteine deprivation could be enhanced by COX7A1 overexpression.