SMARCC1 and glioblastoma: We further studied glioblastoma cell lines and found that when SMARCC2 was specifically knocked out, western blot confirmed that the expression of other subunits of the complex (such as SMARCA4/SMARCC1/SMARCB1) was downregulated, and the re-expression of SMARCC2 resulted in a significant increase in the protein level of many SWI/SNF subunits (Fig. 1F).