SMARCC2 and rhabdoid tumor: On the other hand, a region of SMARCB1 (AA 169–385, SMARCB1 (169–385)) and the SWIRM domain of SMARCC2 (AA 423–518, SMARCC2 (423–518)) form a stabilizer complex, and the inactivation of SMARCB1 has been reported in almost all malignant rhabdoid tumors.