ITGAM and neoplasm: As indicated in previous reports, CD11b activation results in modulation of the myeloid compartment and reprogramming of macrophages.[11a] Specifically, a drastic decrease in M2 macrophages in tumor tissues and a simultaneous increase in the ratio between M1 to M2 macrophages were reported, inducing an antitumor response.[11, 16] Upon treatment, we found a marked decrease in macrophages, which is in line with previous reports,[11, 16] and our future analyses will shed light on our 3D model's ratio between M1 and M2 macrophages.