CDH1 and neoplasm: BxPC‐3 cells isolated from a patient with no evidence of metastatic spread[44] represent an epithelial phenotype with high expression of E‐cadherin.[45] MIAPaCa‐2 cells represent a mesenchymal phenotype derived from a patient with detectable tumor infiltrates in the periaortic area[44] and have high levels of vimentin.[45] Both PDAC cell lines proliferated well when grown encapsulated in starPEG–heparin hydrogels.